Patched (PTCH) Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP7733a
Background:
Ptch a member of the patched gene family. This protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. It functions as a tumor suppressor. Mutations of the Ptch gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly.
Other Names:
Protein patched homolog 1, PTC, PTC1, PTCH1, PTCH
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7733a was selected from the Human region of human Ptch (Human N-term). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PTCH1
Gene ID: 5727
Primary Accession: Q13635
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Ptch a member of the patched gene family. This protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. It functions as a tumor suppressor. Mutations of the Ptch gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly.
Other Names:
Protein patched homolog 1, PTC, PTC1, PTCH1, PTCH
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7733a was selected from the Human region of human Ptch (Human N-term). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PTCH1
Gene ID: 5727
Primary Accession: Q13635
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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