PAWR Polyclonal Antibody

Background:
The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism

Synonyms:
2310001G03Rik, PAR 4, PAR-4, Pawr, PAWR, PRKC Apoptosis WT1 Regulator, PRKC apoptosis WT1 regulator protein, Prostate apoptosis response 4 protein, Prostate apoptosis response protein 4, prostate apoptosis response protein PAR-4, Transcriptional repressor Par-4-like protein PAWR, Transcriptional repressor PAR4, WT1 Interacting Protein

Immunogen: Synthetic peptide of human PAWR

Swissprot: Q96IZ0
Gene Accession: NP_002574

Calculated MW: 37 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: WB 1:1000-1:3000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-1249/sc-1807