Pax-2 polyclonal, anti-human, mouse, rat, pig, rabbit, sheep, bovine, dog, horse, chicken

Protein Family: Transcription Factors

Pathway and Disease: Transcription, Cell Growth and Death

Description:
Paired box protein Pax-2 (Pax-2) is a transcription factor involved in kidney cell differentiation. Pax-2 plays a role in the development of the urogenital tract, the eyes, and the CNS. Defects in Pax-2 are the cause of renal-coloboma syndrome (RCS), also known as papillorenal syndrome or optic nerve coloboma with renal disease. RCS is an autosomal dominant disease characterized by the association of renal hypoplasia, vesicoureteral reflux and dysplasia of the retina and optic disk.

Alternate Names: PAX2, Paired box protein Pax-2, Paired box gene 2

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: Q02962

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Pax-2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.