Pax-3 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6686
Background:
Pax-3 is a protein containing both a paired domain and a paired-type homeodomain. During early neurogenesis, Pax-3 expression is limited to mitotic cells in the ventricular zone of the developing spinal cord and to distinct regions in the hindbrain, midbrain and diencephalon. In 10-12 day embryos, expression of Pax-3 is also seen in neural crest cells of the developing spinal ganglia, the craniofacial mesectoderm and in limb mesenchyme. Mutations in the MITF and Pax-3 genes, encoding transcription factors, are responsible for Waardenburg syndrome II (WSII) and WSI/WSIII, respectively.
Alternative Name:
Paired box protein Pax-3, HuP2, PAX3, HUP2
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: PAX3 polyclonal antibody detects endogenous levels of PAX3 protein.
Immunogen:
Recombinant full length Human Pax-3.
MW: ~ 53 kDa
Swis Prot.: P23760
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Pax-3 is a protein containing both a paired domain and a paired-type homeodomain. During early neurogenesis, Pax-3 expression is limited to mitotic cells in the ventricular zone of the developing spinal cord and to distinct regions in the hindbrain, midbrain and diencephalon. In 10-12 day embryos, expression of Pax-3 is also seen in neural crest cells of the developing spinal ganglia, the craniofacial mesectoderm and in limb mesenchyme. Mutations in the MITF and Pax-3 genes, encoding transcription factors, are responsible for Waardenburg syndrome II (WSII) and WSI/WSIII, respectively.
Alternative Name:
Paired box protein Pax-3, HuP2, PAX3, HUP2
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: PAX3 polyclonal antibody detects endogenous levels of PAX3 protein.
Immunogen:
Recombinant full length Human Pax-3.
MW: ~ 53 kDa
Swis Prot.: P23760
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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