Pax-6 polyclonal, anti-human, mouse, rat
€422.00
In stock
SKU
251935
Protein Family: Transcription Factors
Pathway and Disease: Signaling Molecules and Interaction, Transcription
Description:
Paired box protein (Pax-6) is a transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Pax-6 is required for the differentiation of pancreatic islet alpha cells, and competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Pax-6 regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains. Defects in Pax-6 are associated with a number of diseases and abnormalities of the eye and optic nerve.
Alternate Names: Paired box protein Pax-6, Oculorhombin, Aniridia type II protein, PAX6, AN2
Application Notes: E: 1:10,000-1:50,000; WB: 1:100-1:1,000
Accession No.: P26367
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Pax-6.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Li W et al. 2012. Invest Opthalmol Vis Sci. 50:5334-5343. PMID# 22736612.
Pathway and Disease: Signaling Molecules and Interaction, Transcription
Description:
Paired box protein (Pax-6) is a transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Pax-6 is required for the differentiation of pancreatic islet alpha cells, and competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Pax-6 regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains. Defects in Pax-6 are associated with a number of diseases and abnormalities of the eye and optic nerve.
Alternate Names: Paired box protein Pax-6, Oculorhombin, Aniridia type II protein, PAX6, AN2
Application Notes: E: 1:10,000-1:50,000; WB: 1:100-1:1,000
Accession No.: P26367
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Pax-6.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Li W et al. 2012. Invest Opthalmol Vis Sci. 50:5334-5343. PMID# 22736612.
| Is Featured? | No |
|---|
Write Your Own Review