PAX3 polyclonal, anti-human

Background:
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

Other Names:
Paired box protein Pax-3, HuP2, PAX3, HUP2

Antigen Types:
Synthetic Peptide

Gene Name:
PAX3
Gene ID:
5077
Primary Accession: P23760
Other Accession: NP_852126;5077;18505 (mouse); 114502 (rat);