PAX6 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8841
Background:
This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alternative Name:
Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6, AN2
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: PAX6 polyclonal antibody detects endogenous levels of PAX6 protein.
Immunogen:
Recombinant full length Human PAX6.
MW: ~ 47kDa
Swis Prot.: P26367
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alternative Name:
Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6, AN2
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: PAX6 polyclonal antibody detects endogenous levels of PAX6 protein.
Immunogen:
Recombinant full length Human PAX6.
MW: ~ 47kDa
Swis Prot.: P26367
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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