PAX6 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.

Synonyms: AN, AN2, ASGD5, D11S812E, FVH1, MGDA, WAGR

Cellular Location: Nucleus

Immunogen:
Recombinant protein of human PAX6

Gene Symbol: PAX6

Gene ID: 5080

Swiss prot: P26367

Calculated MW: 47kDa

Recommended dilution:
WB 1:500-2000, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.