PAX7 polyclonal, anti-human, mouse, rat

Background:
The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Alternative Name:
PAX7, FLJ37460, HUP1, OTTHUMP00000002534, Paired box 7, Paired box gene 7, Paired box homeotic gene 7, Paired box protein Pax-7, Paired domain gene 7, Paired domain gene HuP1, Pax7, PAX7 transcriptional factor, PAX7/FKHR fusion gene, included, PAX7, PAX7B, RGD1564360, RMS2,

Application Dilution:
WB:1:1,000
FC:1:50-1:100

Specificity: PAX7 polyclonal antibody detects endogenous levels of PAX7 protein.

Immunogen:
recombinant protein

MW: 57 kDa

Swiss-Prot: P23759(Human) P47239(Mouse) Unigene:226327(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.