PAX8 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.

Synonyms: Paired box protein Pax-8

Cellular Location: Nucleus

Immunogen:
Recombinant protein of human PAX8

Gene Symbol: PAX8

Gene ID: 7849

Swiss prot: Q06710

Calculated MW: 48kDa

Recommended dilution:
WB 1:200-1000, IHC 1:15-50,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.