PAX8 Polyclonal Antibody

Background:
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Neuroscience

Synonyms:
PAX8

Immunogen: Recombinant fusion protein of human PAX8 (NP_003457.1).

Swissprot: Q06710
Gene ID: 7849

Calculated MW: 31 kDa/34 kDa/41 kDa/43 kDa/48 kDa
Observed MW: 51 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.