PAX9 polyclonal, anti-human, mouse, rat

Background:
Pax genes contain paired domains with strong homology to genes in Droso-phila which are involved in programming early development. Pax-9, a member of the paired box-containing gene family, is closely related in its paired do-main to Pax-1. The Pax-9 gene encodes the highly conserved paired domain and the gene is a member of the same subgroup as Pax-1/undulated. Pax-9 is essential for the development of a variety of organs and skeletal elements. Mutations in either the Pax-1 or the Pax-9 genes may produce an inherited skeletal disorder such as the Jarcho-Levin syndrome or other forms of spondylocostal dysplasia, conditions resembling “undulated” in the mouse. A frameshift mutation within the paired domain of Pax-9 was identified in a family segregating autosomal dominant oligodontia whose members had normal primary dentition but lacked most permanent molars. In addition to lack of permanent molars, some individuals also lacked maxillary and/or mandibular second premolars, as well as mandibular central incisors. The gene which encodes Pax-9 maps to human chromosome 14q12-q13.

Alternative Name:
PAX9, Paired box 9, Paired box gene 9, Paired box homeotic gene 9, Paired box protein 9, Paired box protein Pax 9, Paired box protein Pax-9, Paired box protein Pax9, Paired domain gene 9, PAX 9, PAX9, PAX9, STHAG3,

Application Dilution:
WB:1:1,000-1:2,000

Specificity: PAX9 polyclonal antibody detects endogenous levels of PAX9 protein.

Immunogen:
recombinant protein

MW: 36 kDa

Swiss-Prot: P55771(Human) P47242(Mouse) Q2L4T2(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.