PBK polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Lymphokine-activated killer T-cell-originated protein kinase, also known as TOPK or PBK, is an enzyme that in humans is encoded by the PBK gene. The protein encoded by this gene is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. It is mapped to 8p21.1. PBK can mediate cell growth through histone H3 modification. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis.

Description:
Rabbit IgG polyclonal antibody for Lymphokine-activated killer T-cell-originated protein kinase (PBK) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
Cancer/testis antigen 84 antibody, CT84 antibody, Epididymis luminal protein 164 antibody, FLJ14385 antibody, HEL164 antibody, Lymphokine activated killer T cell originated protein kinase antibody, Lymphokine-activated killer T-cell-originated protein kinase antibody, MAPKK like protein kinase antibody, MAPKK-like protein kinase antibody, Nori 3 antibody, Nori-3 antibody, Nori3 antibody, PBK antibody, PDZ binding kinase antibody, PDZ-binding kinase antibody, Serine/threonine protein kinase antibody, Spermatogenesis related protein kinase antibody, Spermatogenesis-related protein kinase antibody, SPK antibody, T LAK cell originated protein kinase antibody, T-LAK cell-originated protein kinase antibody, TOPK antibody, TOPK_HUMAN antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human PBK recombinant protein (Position: N71-V322). Human PBK shares 89% amino acid (aa) sequence identity with mouse PBK.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.