PBK Polyclonal Antibody

Background:
PBK(PDZ-binding kinase) is also named as TOPK, CT84, Nori-3, SPK and belongs to the MAP kinase kinase subfamily. PBK may have a role in the regulation of cellular proliferation and progression of the cell cycle. It has a characteristic cdc2ycyclin B phosphorylation site(SyT-P-X-KyR) at its N terminus,which is conserved across species, and it is phosphorylated in a cell cycle-dependent manner at mitosis, and that this phosphorylation is required for its activation.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signaling transduction

Synonyms:
Cancer/testis antigen 84, CT84, Epididymis luminal protein 164, FLJ14385, HEL164, Lymphokine activated killer T cell originated protein kinase, Lymphokine-activated killer T-cell-originated protein kinase, MAPKK like protein kinase, MAPKK-like protein kinase, Nori 3, Nori-3, Nori3, PBK, PDZ binding kinase, PDZ-binding kinase, Serine/threonine protein kinase, Spermatogenesis related protein kinase, Spermatogenesis-related protein kinase, SPK, T LAK cell originated protein kinase, T-LAK cell-originated protein kinase, TOPK, TOPK

Immunogen: Recombinant Human Lymphokine-activated killer T-cell-originated protein kinase protein

Swissprot: Q96KB5

Calculated MW: 36 kDa
Observed MW: 40 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Concentration: 2 mg/mL
Dilution: WB 1:500-1:1000, IHC 1:50-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-15243-R