PBXIP1 Polyclonal Antibody

Background:
The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.

Research Area: Epigenetics and Nuclear Signaling, Signal transduction

Synonyms:
4732463H20Rik, Hematopoietic PBX interacting protein , HPIP , MGC38361, Pre B cell leukemia homeobox interacting protein 1, RP11-307C12.2

Immunogen: Fusion protein of human PBXIP1

Swissprot: Q96AQ6
Gene Accession: BC016852

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.66 mg/mL
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.