PBXIP1 Polyclonal Antibody

Background:
The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.

Research Area: Epigenetics and Nuclear Signaling, Signal transduction

Synonyms:
PBXIP1, HPIP

Immunogen: Recombinant fusion protein of human PBXIP1 (NP_065385.2).

Swissprot: Q96AQ6
Gene ID: 57326

Calculated MW: 72 kDa/77 kDa/80 kDa
Observed MW: 110 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:1000-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.