PC Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12494a
Background:
This gene encodes pyruvate carboxylase, which requiresbiotin and ATP to catalyse the carboxylation of pyruvate tooxaloacetate. The active enzyme is a homotetramer arranged in atetrahedron which is located exclusively in the mitochondrialmatrix. Pyruvate carboxylase is involved in gluconeogenesis,lipogenesis, insulin secretion and synthesis of theneurotransmitter glutamate. Mutations in this gene have beenassociated with pyruvate carboxylase deficiency. Alternativelyspliced transcript variants with different 5' UTRs, but encodingthe same protein, have been found for this gene. [provided byRefSeq].
Other Names:
Pyruvate carboxylase, mitochondrial, Pyruvic carboxylase, PCB, PC
Gene Name: PC (HGNC:8636)
Gene ID: 5091
Primary Accession: P11498
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes pyruvate carboxylase, which requiresbiotin and ATP to catalyse the carboxylation of pyruvate tooxaloacetate. The active enzyme is a homotetramer arranged in atetrahedron which is located exclusively in the mitochondrialmatrix. Pyruvate carboxylase is involved in gluconeogenesis,lipogenesis, insulin secretion and synthesis of theneurotransmitter glutamate. Mutations in this gene have beenassociated with pyruvate carboxylase deficiency. Alternativelyspliced transcript variants with different 5' UTRs, but encodingthe same protein, have been found for this gene. [provided byRefSeq].
Other Names:
Pyruvate carboxylase, mitochondrial, Pyruvic carboxylase, PCB, PC
Gene Name: PC (HGNC:8636)
Gene ID: 5091
Primary Accession: P11498
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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