PC-PLD3 rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2014],catalytic activity:A phosphatidylcholine + H(2)O = choline + a phosphatidate.,PTM:Glycosylated.,similarity:Belongs to the phospholipase D family.,similarity:Contains 2 PLD phosphodiesterase domains.,tissue specificity:Widely expressed. Expressec at higher level in brain. Expresse at low level in corpus callosum, suggsting that it is highly expressed in neurons.,

Synonyms: PLD3, Phospholipase D3, PLD 3, Choline phosphatase 3, HindIII K4L homolog, Hu-K4, Phosphatidylcholine-hydrolyzing phospholipase D3

Gene Name: PLD3

Gene ID: 23646

SwissProt ID: Q8IV08

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.