PC polyclonal (N-term), anti-human, mouse
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In stock
SKU
AC-AP12494A
Catalog Number: AC-AP12494A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31105
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31105
Applications: IHC-P, WB
Datasheet
Request Information
Background:
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq].
Other Names:
Pyruvate carboxylase, mitochondrial, Pyruvic carboxylase, PCB, PC
Target/Specificity:
This PC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 amino acids from the N-terminal region of human PC.
Antigen Region:
53-82
Antigen Type: Synthetic Peptide
Gene Name: PC (HGNC:8636)
Gene ID: 5091
Primary Accession: P11498
NCBI Accession: NP_000911.2;NP_001035806.1;NP_071504.2
Other Accession: P52873; Q05920; Q29RK2; NP_001035806.1; NP_000911.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq].
Other Names:
Pyruvate carboxylase, mitochondrial, Pyruvic carboxylase, PCB, PC
Target/Specificity:
This PC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 amino acids from the N-terminal region of human PC.
Antigen Region:
53-82
Antigen Type: Synthetic Peptide
Gene Name: PC (HGNC:8636)
Gene ID: 5091
Primary Accession: P11498
NCBI Accession: NP_000911.2;NP_001035806.1;NP_071504.2
Other Accession: P52873; Q05920; Q29RK2; NP_001035806.1; NP_000911.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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