PC11X Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
This gene belongs to the protocadherin gene family| a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats| a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog| despite divergence leading to coding region changes| is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia. Alternative splicing results in multiple transcript variants.

Research Area: Neuroscience, Signal transduction

Synonyms: PC11X

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year