PCBD1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.

Synonyms: PCD, PHS, DCOH, PCBD

Cellular Location: Cytoplasm Nucleus

Immunogen:
Recombinant protein of human PCBD1

Gene Symbol: PCBD1

Gene ID: 5092

Swiss prot: P61457

Calculated MW: 12kDa

Recommended dilution:
WB 1:500-2000, IHC 1:25-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.