PCBD1 Polyclonal Antibody

Background:
This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction

Synonyms:
PCBD1, DCOH, PCBD, PCD, PHS

Immunogen: Recombinant fusion protein of human PCBD1 (NP_000272.1).

Swissprot: P61457
Gene ID: 5092

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IF 1:10-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.