PCBP1 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP18827c
Background:
This intronless gene is thought to have been generated byretrotransposition of a fully processed PCBP-2 mRNA. This gene andPCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to havearisen as a result of duplication events of entire genes. Theprotein encoded by this gene appears to be multifunctional. Italong with PCBP-2 and hnRNPK corresponds to the major cellularpoly(rC)-binding protein. It contains three K-homologous (KH)domains which may be involved in RNA binding. This encoded proteintogether with PCBP-2 also functions as translational coactivatorsof poliovirus RNA via a sequence-specific interaction withstem-loop IV of the IRES and promote poliovirus RNA replication bybinding to its 5'-terminal cloverleaf structure. It has also beenimplicated in translational control of the 15-lipoxygenase mRNA,human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA.The encoded protein is also suggested to play a part in formationof a sequence-specific alpha-globin mRNP complex which isassociated with alpha-globin mRNA stability.
Other Names:
Poly(rC)-binding protein 1, Alpha-CP1, Heterogeneous nuclear ribonucleoprotein E1, hnRNP E1, Nucleic acid-binding protein SUB23, PCBP1
Gene Name: PCBP1 {ECO:0000303|PubMed:7607214, ECO:0000312|HGNC:HGNC:8647}
Gene ID: 5093
Primary Accession: Q15365
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This intronless gene is thought to have been generated byretrotransposition of a fully processed PCBP-2 mRNA. This gene andPCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to havearisen as a result of duplication events of entire genes. Theprotein encoded by this gene appears to be multifunctional. Italong with PCBP-2 and hnRNPK corresponds to the major cellularpoly(rC)-binding protein. It contains three K-homologous (KH)domains which may be involved in RNA binding. This encoded proteintogether with PCBP-2 also functions as translational coactivatorsof poliovirus RNA via a sequence-specific interaction withstem-loop IV of the IRES and promote poliovirus RNA replication bybinding to its 5'-terminal cloverleaf structure. It has also beenimplicated in translational control of the 15-lipoxygenase mRNA,human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA.The encoded protein is also suggested to play a part in formationof a sequence-specific alpha-globin mRNP complex which isassociated with alpha-globin mRNA stability.
Other Names:
Poly(rC)-binding protein 1, Alpha-CP1, Heterogeneous nuclear ribonucleoprotein E1, hnRNP E1, Nucleic acid-binding protein SUB23, PCBP1
Gene Name: PCBP1 {ECO:0000303|PubMed:7607214, ECO:0000312|HGNC:HGNC:8647}
Gene ID: 5093
Primary Accession: Q15365
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review