PCCA Polyclonal Antibody

Background:
The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area: Metabolism, Signal Transduction

Synonyms:
PCCA

Immunogen: Recombinant fusion protein of human PCCA (NP_000273.2).

Swissprot: P05165
Gene ID: 5095

Calculated MW: 75 kDa/77 kDa/80 kDa
Observed MW: 80 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:1000-1:3000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.