PCCA polyclonal (Center), anti-human, rat

PCCA polyclonal (Center), anti-human, rat

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In stock
SKU
AC-AP12328c
Catalog Number: AC-AP12328c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31944
Applications: WB, IHC-P
Datasheet

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Background:
The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.

Other Names:
Propionyl-CoA carboxylase alpha chain, mitochondrial, PCCase subunit alpha, Propanoyl-CoA:carbon dioxide ligase subunit alpha, PCCA

Target/Specificity:
This PCCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 362-390 amino acids from the Central region of human PCCA.

Antigen Region:
362-390

Antigen Type: Synthetic Peptide

Gene Name: PCCA (HGNC:8653)
Gene ID: 5095
Primary Accession: P05165
NCBI Accession: NP_000273.2;NP_001121164.1;NP_001171475.1
Other Accession: NP_001121164.1;NP_000273.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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