PCDHA12 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP13139A
Catalog Number: AC-AP13139A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32533
Applications: IHC-P, WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32533
Applications: IHC-P, WB
Datasheet
Request Information
Background:
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Other Names:
Protocadherin alpha-12, PCDH-alpha-12, PCDHA12
Target/Specificity:
This PCDHA12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the N-terminal region of human PCDHA12.
Antigen Region:
166-194
Antigen Type: Synthetic Peptide
Gene Name: PCDHA12
Gene ID: 56137
Primary Accession: Q9UN75
NCBI Accession: NP_061726.1;NP_114070.1
Other Accession: NP_061726.1;NP_114070.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Other Names:
Protocadherin alpha-12, PCDH-alpha-12, PCDHA12
Target/Specificity:
This PCDHA12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the N-terminal region of human PCDHA12.
Antigen Region:
166-194
Antigen Type: Synthetic Peptide
Gene Name: PCDHA12
Gene ID: 56137
Primary Accession: Q9UN75
NCBI Accession: NP_061726.1;NP_114070.1
Other Accession: NP_061726.1;NP_114070.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review