PCDHAC2 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP12157C
Catalog Number: AC-AP12157C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31967
Applications: FC, IF, IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31967
Applications: FC, IF, IHC-P, WB
Datasheet
Request Information
Background:
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Other Names:
Protocadherin alpha-C2, PCDH-alpha-C2, PCDHAC2
Target/Specificity:
This PCDHAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 616-644 amino acids from the Central region of human PCDHAC2.
Antigen Region:
616-644
Antigen Type: Synthetic Peptide
Gene Name: PCDHAC2
Gene ID: 56134
Primary Accession: Q9Y5I4
NCBI Accession: NP_061722.1;NP_114089.1
Other Accession: NP_114089.1;NP_061722.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Other Names:
Protocadherin alpha-C2, PCDH-alpha-C2, PCDHAC2
Target/Specificity:
This PCDHAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 616-644 amino acids from the Central region of human PCDHAC2.
Antigen Region:
616-644
Antigen Type: Synthetic Peptide
Gene Name: PCDHAC2
Gene ID: 56134
Primary Accession: Q9Y5I4
NCBI Accession: NP_061722.1;NP_114089.1
Other Accession: NP_114089.1;NP_061722.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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