PCDHB16 antibody (clone 3H1), anti-human
€435.00
In stock
SKU
AC-AT3224a
Catalog Number: AC-AT3224a
Size: 50 µg
Isotype: mouse IgG2b Kappa
Applications: WB
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Size: 50 µg
Isotype: mouse IgG2b Kappa
Applications: WB
Request Information AC-AT3224a">Request Information
Background:
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Other Names:
Protocadherin beta-16, PCDH-beta-16, Protocadherin-3X, PCDHB16, KIAA1621, PCDH3X
Antigen Type:
Recombinant Protein
Gene Name: PCDHB16 (HGNC:14546)
Gene ID: 57717
NCBI Accession: NP_066008.1
Primary Accession: Q9NRJ7
Other Accession: BC036062
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Other Names:
Protocadherin beta-16, PCDH-beta-16, Protocadherin-3X, PCDHB16, KIAA1621, PCDH3X
Antigen Type:
Recombinant Protein
Gene Name: PCDHB16 (HGNC:14546)
Gene ID: 57717
NCBI Accession: NP_066008.1
Primary Accession: Q9NRJ7
Other Accession: BC036062
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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