PCDHB3 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP12159a
Catalog Number: AC-AP12159a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31977
Applications: IF, IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31977
Applications: IF, IHC-P, WB
Datasheet
Request Information
Background:
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Other Names:
Protocadherin beta-3, PCDH-beta-3, PCDHB3
Target/Specificity:
This PCDHB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of human PCDHB3.
Antigen Region:
12-39
Antigen Type: Synthetic Peptide
Gene Name: PCDHB3
Gene ID: 56132
Primary Accession: Q9Y5E6
NCBI Accession: NP_061760.1
Other Accession: NP_061760.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Other Names:
Protocadherin beta-3, PCDH-beta-3, PCDHB3
Target/Specificity:
This PCDHB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of human PCDHB3.
Antigen Region:
12-39
Antigen Type: Synthetic Peptide
Gene Name: PCDHB3
Gene ID: 56132
Primary Accession: Q9Y5E6
NCBI Accession: NP_061760.1
Other Accession: NP_061760.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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