PCDHB5 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP13230c
Background:
This gene is a member of the protocadherin beta genecluster, one of three related gene clusters tandemly linked onchromosome five. The gene clusters demonstrate an unusual genomicorganization similar to that of B-cell and T-cell receptor geneclusters. The beta cluster contains 16 genes and 3 pseudogenes,each encoding 6 extracellular cadherin domains and a cytoplasmictail that deviates from others in the cadherin superfamily. Theextracellular domains interact in a homophilic manner to specifydifferential cell-cell connections. Unlike the alpha and gammaclusters, the transcripts from these genes are made up of only onelarge exon, not sharing common 3' exons as expected. These neuralcadherin-like cell adhesion proteins are integral plasma membraneproteins. Their specific functions are unknown but they most likelyplay a critical role in the establishment and function of specificcell-cell neural connections.
Other Names:
Protocadherin beta-5, PCDH-beta-5, PCDHB5
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13230c was selected from the Center region of PCDHB5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PCDHB5
Gene ID: 26167
Primary Accession: Q9Y5E4
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene is a member of the protocadherin beta genecluster, one of three related gene clusters tandemly linked onchromosome five. The gene clusters demonstrate an unusual genomicorganization similar to that of B-cell and T-cell receptor geneclusters. The beta cluster contains 16 genes and 3 pseudogenes,each encoding 6 extracellular cadherin domains and a cytoplasmictail that deviates from others in the cadherin superfamily. Theextracellular domains interact in a homophilic manner to specifydifferential cell-cell connections. Unlike the alpha and gammaclusters, the transcripts from these genes are made up of only onelarge exon, not sharing common 3' exons as expected. These neuralcadherin-like cell adhesion proteins are integral plasma membraneproteins. Their specific functions are unknown but they most likelyplay a critical role in the establishment and function of specificcell-cell neural connections.
Other Names:
Protocadherin beta-5, PCDH-beta-5, PCDHB5
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13230c was selected from the Center region of PCDHB5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PCDHB5
Gene ID: 26167
Primary Accession: Q9Y5E4
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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