PCDHB5 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP13230c
Catalog Number: AC-AP13230c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33054
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33054
Applications: IHC-P, WB
Datasheet
Request Information
Background:
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Other Names:
Protocadherin beta-5, PCDH-beta-5, PCDHB5
Target/Specificity:
This PCDHB5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-307 amino acids from the Central region of human PCDHB5.
Antigen Region:
278-307
Antigen Type: Synthetic Peptide
Gene Name: PCDHB5
Gene ID: 26167
Primary Accession: Q9Y5E4
NCBI Accession: NP_056484.1
Other Accession: NP_056484.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Other Names:
Protocadherin beta-5, PCDH-beta-5, PCDHB5
Target/Specificity:
This PCDHB5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-307 amino acids from the Central region of human PCDHB5.
Antigen Region:
278-307
Antigen Type: Synthetic Peptide
Gene Name: PCDHB5
Gene ID: 26167
Primary Accession: Q9Y5E4
NCBI Accession: NP_056484.1
Other Accession: NP_056484.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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