PCDHB7 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13605b
Background:
This gene is a member of the protocadherin beta genecluster, one of three related gene clusters tandemly linked onchromosome five. The gene clusters demonstrate an unusual genomicorganization similar to that of B-cell and T-cell receptor geneclusters. The beta cluster contains 16 genes and 3 pseudogenes,each encoding 6 extracellular cadherin domains and a cytoplasmictail that deviates from others in the cadherin superfamily. Theextracellular domains interact in a homophilic manner to specifydifferential cell-cell connections. Unlike the alpha and gammaclusters, the transcripts from these genes are made up of only onelarge exon, not sharing common 3' exons as expected. These neuralcadherin-like cell adhesion proteins are integral plasma membraneproteins. Their specific functions are unknown but they most likelyplay a critical role in the establishment and function of specificcell-cell neural connections. The transcript for this particularfamily member uses more than one polyadenylation site. [provided byRefSeq].
Other Names:
Protocadherin beta-7, PCDH-beta-7, PCDHB7
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13605b was selected from the C-term region of PCDHB7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PCDHB7
Gene ID: 56129
Primary Accession: Q9Y5E2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene is a member of the protocadherin beta genecluster, one of three related gene clusters tandemly linked onchromosome five. The gene clusters demonstrate an unusual genomicorganization similar to that of B-cell and T-cell receptor geneclusters. The beta cluster contains 16 genes and 3 pseudogenes,each encoding 6 extracellular cadherin domains and a cytoplasmictail that deviates from others in the cadherin superfamily. Theextracellular domains interact in a homophilic manner to specifydifferential cell-cell connections. Unlike the alpha and gammaclusters, the transcripts from these genes are made up of only onelarge exon, not sharing common 3' exons as expected. These neuralcadherin-like cell adhesion proteins are integral plasma membraneproteins. Their specific functions are unknown but they most likelyplay a critical role in the establishment and function of specificcell-cell neural connections. The transcript for this particularfamily member uses more than one polyadenylation site. [provided byRefSeq].
Other Names:
Protocadherin beta-7, PCDH-beta-7, PCDHB7
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13605b was selected from the C-term region of PCDHB7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PCDHB7
Gene ID: 56129
Primary Accession: Q9Y5E2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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