PCDHGB1 polyclonal (C-term), anti-human

Background:
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Other Names:
Protocadherin gamma-B1, PCDH-gamma-B1, PCDHGB1

Target/Specificity:
This PCDHGB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 773-799 amino acids from the C-terminal region of human PCDHGB1.

Antigen Region:
773-799

Antigen Type: Synthetic Peptide

Gene Name: PCDHGB1
Gene ID: 56104
Primary Accession: Q9Y5G3
NCBI Accession: NP_061745.1;NP_115266.1
Other Accession: NP_061745.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.