PCGF2 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP14911c
Background:
The protein encoded by this gene contains a RING fingermotif and is similar to the polycomb group (PcG) gene products. PcGgene products form complexes via protein-protein interaction andmaintain the transcription repression of genes involved inembryogenesis, cell cycles, and tumorigenesis. This protein wasshown to act as a negative regulator of transcription and has tumorsuppressor activity. The expression of this gene was detected invarious tumor cells, but is limited in neural organs in normaltissues. Knockout studies in mice suggested that this protein maynegatively regulate the expression of different cytokines,chemokines, and chemokine receptors, and thus plays an importantrole in lymphocyte differentiation and migration, as well as inimmune responses.
Other Names:
Polycomb group RING finger protein 2, DNA-binding protein Mel-18, RING finger protein 110, Zinc finger protein 144, PCGF2, MEL18, RNF110, ZNF144
Gene Name: PCGF2
Gene ID: 7703
Primary Accession: P35227
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene contains a RING fingermotif and is similar to the polycomb group (PcG) gene products. PcGgene products form complexes via protein-protein interaction andmaintain the transcription repression of genes involved inembryogenesis, cell cycles, and tumorigenesis. This protein wasshown to act as a negative regulator of transcription and has tumorsuppressor activity. The expression of this gene was detected invarious tumor cells, but is limited in neural organs in normaltissues. Knockout studies in mice suggested that this protein maynegatively regulate the expression of different cytokines,chemokines, and chemokine receptors, and thus plays an importantrole in lymphocyte differentiation and migration, as well as inimmune responses.
Other Names:
Polycomb group RING finger protein 2, DNA-binding protein Mel-18, RING finger protein 110, Zinc finger protein 144, PCGF2, MEL18, RNF110, ZNF144
Gene Name: PCGF2
Gene ID: 7703
Primary Accession: P35227
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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