PCK1 / PEPCKC (internal region) polyclonal, anti-human

Background:
This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.

Other Names:
Phosphoenolpyruvate carboxykinase, cytosolic [GTP], PEPCK-C, 4.1.1.32, PCK1, PEPCK1

Antigen Types:
Synthetic Peptide

Gene Name:
PCK1 {ECO:0000303|PubMed:8490617, ECO:0000312|HGNC:HGNC:8724}
Gene ID:
5105
Primary Accession: P35558
Other Accession: NP_002582;5105;