PCK1 polyclonal, anti-human, mouse, rat

Background:
This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.

Synonyms: PEPCK-C, PEPCK1, PEPCKC

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human PCK1

Gene Symbol: PCK1

Gene ID: 5105

Swiss prot: P35558

Calculated MW: 69kDa

Recommended dilution:
WB 1:1000-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.