PCLAF Polyclonal Antibody

Background:
PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.

Research Area: Cancer, Cell Biology, Metabolism

Synonyms:
HCV NS5A transactivated protein 9 , HCV NS5A-transactivated protein 9, Hepatitis C virus NS5A transactivated protein 9, Hepatitis C virus NS5A-transactivated protein 9, KIAA0101, L5, NS5 ATP9, NS5ATP9, OEATC 1, OEATC, OEATC-1, OEATC1, Overexpressed in anaplastic thyroid carcinoma 1, p15(PAF), p15PAF, PAF, PAF, PCNA associated factor, PCNA-associated factor

Immunogen: Synthetic peptide of human PCLAF

Swissprot: Q15004
Gene Accession: NP055551

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.08 mg/mL
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.