PCMT1 antibody (clone 1D6), anti-human, mouse, rat
€435.00
In stock
SKU
AC-AT3235a
Catalog Number: AC-AT3235a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, Ehttps://www.abcepta.com/products/pdf_download/AT3235a-PCMT1-Antibody-monoclonal-M02">Request Information AC-AT3235a">Request Information
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, Ehttps://www.abcepta.com/products/pdf_download/AT3235a-PCMT1-Antibody-monoclonal-M02">Request Information AC-AT3235a">Request Information
Background:
Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.
Other Names:
Protein-L-isoaspartate(D-aspartate) O-methyltransferase, PIMT, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl/D-aspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PCMT1
Antigen Type:
Recombinant Protein
Gene Name: PCMT1
Gene ID: 5110
NCBI Accession: NP_001238978.1;NP_001238982.1
Primary Accession: P22061
Other Accession: NM_005389
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.
Other Names:
Protein-L-isoaspartate(D-aspartate) O-methyltransferase, PIMT, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl/D-aspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PCMT1
Antigen Type:
Recombinant Protein
Gene Name: PCMT1
Gene ID: 5110
NCBI Accession: NP_001238978.1;NP_001238982.1
Primary Accession: P22061
Other Accession: NM_005389
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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