PCMT1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms: PIMT

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human PCMT1

Gene Symbol: PCMT1

Gene ID: 5110

Swiss prot: P22061

Calculated MW: 25kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-100, IP 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.