PCNA antibody (clone S1), anti-human, mouse, rat

Background:
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

Other Names:
Proliferating cell nuclear antigen, PCNA, Cyclin, PCNA

Antigen Type:
Recombinant Protein

Gene Name: PCNA
Gene ID: 5111
NCBI Accession: NP_002583.1;NP_872590.1
Primary Accession: P12004
Other Accession: BC000491
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .