PCNA (clone 2E1-G10-H10), anti-human, mouse, monkey, rat, hamster

Background:
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta.The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication.In response to DNA damage,this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway.Two transcript variants encoding the same protein have been found for this gene.Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.[provided by RefSeq,Jul 2008]

Synonyms: ATLD2

Cellular Location: Nucleus

Immunogen:
Purified recombinant human PCNA protein fragments expressed in E.coli.

Gene Symbol: PCNA

Gene ID: 5111

Swiss prot: P12004

Calculated MW: 36kDa

Recommended dilution:
WB 1:1000, ICC 1:100

Purity:
Fractional precipitation

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.