PCNA monoclonal (C-term), anti-human, mouse, rat
€0.00
In stock
SKU
AC-AM2237b
Catalog Number: AC-AM2237b
Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 1157CT1.1.3
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 1157CT1.1.3
Applications: WB, IHC-P
Datasheet
Request Information
Background:
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Other Names:
Proliferating cell nuclear antigen, PCNA, Cyclin, PCNA
Target/Specificity:
This PCNA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 236-261 amino acids from the C-terminal region of human PCNA.
Antigen Region:
236-261
Antigen Type: Synthetic Peptide
Gene Name: PCNA
Gene ID: 5111
Primary Accession: P12004
NCBI Accession: NP_002583.1;NP_872590.1
Other Accession: P04961; P61258; P57761; Q3ZBW4
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Other Names:
Proliferating cell nuclear antigen, PCNA, Cyclin, PCNA
Target/Specificity:
This PCNA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 236-261 amino acids from the C-terminal region of human PCNA.
Antigen Region:
236-261
Antigen Type: Synthetic Peptide
Gene Name: PCNA
Gene ID: 5111
Primary Accession: P12004
NCBI Accession: NP_002583.1;NP_872590.1
Other Accession: P04961; P61258; P57761; Q3ZBW4
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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