PCPTP1 polyclonal (N-term), anti-human

PCPTP1 polyclonal (N-term), anti-human

€0.00
In stock
SKU
AC-AP8409a
Catalog Number: AC-AP8409a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB0621
Applications: IHC-P, WB
Datasheet

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Background:
PCPTP1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene for this protein predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of the gene for this protein was reported to be regulated by the nerve growth factor, which suggested a function in neuronal growth and differentiation.

Other Names:
Receptor-type tyrosine-protein phosphatase R, R-PTP-R, Ch-1PTPase, NC-PTPCOM1, Protein-tyrosine phosphatase PCPTP1, PTPRR, ECPTP, PTPRQ

Target/Specificity:
This PCPTP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-265 amino acids from the N-terminal region of human PCPTP1.

Antigen Region:
234-265

Antigen Type: Synthetic Peptide

Gene Name: PTPRR
Gene ID: 5801
Primary Accession: Q15256
NCBI Accession: NP_001193944.1;NP_001193945.1;NP_002840.2;NP_570897.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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