PCSK1 antibody (clone 3D2), anti-human, mouse, rat

PCSK1 antibody (clone 3D2), anti-human, mouse, rat

€435.00
In stock
SKU
AC-AT3239a
Catalog Number: AC-AT3239a
Size: 100 µg
Isotype: mouse IgG3 Kappa
Applications: WB, IHC, IF, Ehttps://www.abcepta.com/products/pdf_download/AT3239a-PCSK1-Antibody-monoclonal-M02">Request Information AC-AT3239a">Request Information
Background:
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.

Other Names:
Neuroendocrine convertase 1, NEC 1, Prohormone convertase 1, Proprotein convertase 1, PC1, PCSK1, NEC1

Antigen Type:
Recombinant Protein

Gene Name: PCSK1
Gene ID: 5122
NCBI Accession: NP_000430.3;NP_001171346.1
Primary Accession: P29120
Other Accession: NM_000439
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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