PCSK4 Antibody (N-term) Blocking Peptide

Background:
Proprotein convertases, including PCSK4, arecalcium-dependent serine proteases related to bacterial subtilisinsand to yeast kexin. These enzymes process precursor proteins totheir active forms by selective cleavage of the polypeptide atsites following paired basic amino acids. In mammals, this familycomprises PC1 (MIM 162150), PC2 (MIM 162151), PC4, PC5 (MIM600488), furin (FUR; MIM 136950), and PACE4 (MIM 167405).Substrates for these enzymes range from prohormones to precursorsfor growth factors to cell surface receptors and viral surfaceglycoproteins (Cao et al., 2001 [PubMed 11776387]).[supplied byOMIM].

Other Names:
Proprotein convertase subtilisin/kexin type 4, 3421-, Proprotein convertase 4, PC4, PCSK4 {ECO:0000312|EMBL:AAH363541}

Gene Name: PCSK4 {ECO:0000312|EMBL:AAH36354.1}

Gene ID: 54760
Primary Accession: Q6UW60
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.