PCSK4 polyclonal (N-term), anti-human

PCSK4 polyclonal (N-term), anti-human

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In stock
SKU
AC-AP16878A
Catalog Number: AC-AP16878A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30368
Applications: WB
Datasheet

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Background:
Proprotein convertases, including PCSK4, arecalcium-dependent serine proteases related to bacterial subtilisinsand to yeast kexin. These enzymes process precursor proteins totheir active forms by selective cleavage of the polypeptide atsites following paired basic amino acids. In mammals, this familycomprises PC1 (MIM 162150), PC2 (MIM 162151), PC4, PC5 (MIM600488), furin (FUR; MIM 136950), and PACE4 (MIM 167405).Substrates for these enzymes range from prohormones to precursorsfor growth factors to cell surface receptors and viral surfaceglycoproteins (Cao et al., 2001 [PubMed 11776387]).[supplied byOMIM].

Other Names:
Proprotein convertase subtilisin/kexin type 4, 3421-, Proprotein convertase 4, PC4, PCSK4 {ECO:0000312|EMBL:AAH363541}

Target/Specificity:
This PCSK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-196 amino acids from the N-terminal region of human PCSK4.

Antigen Region:
168-196

Antigen Type: Synthetic Peptide

Gene Name: PCSK4 {ECO:0000312|EMBL:AAH36354.1}
Gene ID: 54760
Primary Accession: Q6UW60
NCBI Accession: NP_060043.2
Other Accession: NP_060043.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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