PCSK6 polyclonal (C-term), anti-human

PCSK6 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP14833b
Catalog Number: AC-AP14833b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34608
Applications: WB
Datasheet

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Background:
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.

Other Names:
Proprotein convertase subtilisin/kexin type 6, 3421-, Paired basic amino acid cleaving enzyme 4, Subtilisin-like proprotein convertase 4, SPC4, Subtilisin/kexin-like protease PACE4, PCSK6, PACE4

Target/Specificity:
This PCSK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 659-688 amino acids from the C-terminal region of human PCSK6.

Antigen Region:
659-688

Antigen Type: Synthetic Peptide

Gene Name: PCSK6
Gene ID: 5046
Primary Accession: P29122
NCBI Accession: NP_002561.1;NP_612192.1;NP_612193.1;NP_612194.1;NP_612195.1;NP_612196.1;NP_612197.1;NP_612198.2
Other Accession: NP_612197.1;NP_612194.1;NP_612196.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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