PCSK9 polyclonal, anti-human antibody
€295.00
In stock
SKU
AC-ABV10837-100
Catalog Number: AC-ABV10837-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, E
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, E
Datasheet
Request Information
Background:
Proprotein convertase subtilisin/kexin type 9 (PCSK9), is an enzyme which in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A (EGF-A) domain of the low-density lipoprotein receptor (LDLR), inducing LDLR degradation. PCSK9 may also have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a rare form of autosomal dominant familial hypercholesterolemia (HCHOLA3).
Other Names:
PCSK9, FH3, HCHOLA3, LDLCQ1, NARC1, PC9
Primary Accession: Q8NBP7
Gene Name: PCSK9
Gene ID: 255738
Proprotein convertase subtilisin/kexin type 9 (PCSK9), is an enzyme which in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A (EGF-A) domain of the low-density lipoprotein receptor (LDLR), inducing LDLR degradation. PCSK9 may also have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a rare form of autosomal dominant familial hypercholesterolemia (HCHOLA3).
Other Names:
PCSK9, FH3, HCHOLA3, LDLCQ1, NARC1, PC9
Primary Accession: Q8NBP7
Gene Name: PCSK9
Gene ID: 255738
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