PCT (Capture Ab) (clone H6), anti-human

Background:
-Procalcitonin (PCT) is a peptide precursor of the hormone calcitonin, the latter being involved with calcium homeostasis. It is composed of 116 amino acids and is produced by parafollicular cells (C cells) of the thyroid and by the neuroendocrine cells of the lung and the intestine. Measurement of procalcitonin can be used as a marker of severe sepsis caused by bacteria and generally grades well with the degree of sepsis, although levels of procalcitonin in the blood are very low. PCT has the greatest sensitivity (85%) and specificity (91%) for differentiating patients with systemic inflammatory response syndrome (SIRS) from those with sepsis, when compared with IL-2, IL-6, IL-8, CRP and TNF-alpha. It is a biomarker of bacterial infection which may help gauge the severity and prognosis of patients with CAP. In addition to clinical predictors, PCT may assist in decisions pertaining to timing of discharge from hospital and the discontinuation of antibiotics.-

Immunogen:
-Recombinant PCT protein.-

Specificity:
-It specifically recognize the humanPCT.-

Matched antibody pair: -Capture Ab:PCT mAb (clone # H6), Detection Ab:PCT mAb (clone #D6)-

Recommended Application:
-Western Blot, WB; ELISA; Chemilumineseent immunoassay, CLIA; Immunoturbidimetry, ITM-

Product Form: -Liquid-

Purification & Buffer: -Protein A or G purified and supplied in 0.01 M PBS (pH7.4)& 0.15 M NaClwithout preservative.-

Purity: ->95% by HPLC & SDS-PAGE-

Storage Instruction:
-Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.