PD-1 Polyclonal Antibody

Background:
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Research Area: Cancer, Cell Biology, Immunology

Synonyms:
PDCD1, CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1

Immunogen: A synthetic peptide of human PD-1 (NP_005009.2).

Swissprot: Q15116
Gene ID: 5133

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.